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Active Immunization Against 5α-androstane-3α, 17β-diol Increases Ovulation Rate in Merino Ewes OAK
TETSUKA, Masafumi; NANCARROW, Colin. D.; 手塚, 雅文.
Cyclic Merino ewes were immunized three times against 5α−androstane-3α,17β-diol (3α-diol) at three week intervals (weeks 0,3 and 6). After the third immunization, estrous cycles were synchronized by a series of PG injections and intensive blood samples were obtained for gonadotropin analyses during the mid-luteal phase and during the early follicular phase. Ovulation rates were determined after each immunization and subsequent cloprostenol (PG)-induced luteolysis (weeks 3, 6, 8 and 11). After the second immunization, daily blood samples were obtained and concentrations of plasma progesterone (P) were measured. Immunization against 3α-diol significantly increased the ovulation rate after the second and third immunizations and at week 10 (P<0.01,...
Palavras-chave: Ovulation rate; Sheep; Immunization; 5a-reduced androgen.
Ano: 2001 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3033
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